Traductor

29 January 2012

Dr Daniel Uerbelhart and the solutions for the arthritis disease





The dr Daniel Uerbelhart( expert international Valmont Clinical, Switzerland) have speaked in exclusive for NOTICIAS DE SALUD during the presence in Barcelona for a Congress about diseases bornes.




-Can osteoarthritis, some day, disappear or be cured?
--It would be nice but I am not sure that this can really be reached because osteoarthritis is also linked with the aging of the population and more and more people are aging all over the world. So maybe we will have good solutions to prevent the beginning and also the progression but I think it is a utopia to think that we can totally eradicate osteoarthritis.



-The age of those affected by osteoarthritis is paradoxically lowering. Why is that?
--I have the feeling that, in an epidemiologic basis, because you have more and more people having active sport activities with micro to macro traumatisms, and of course this is a clear etiology of osteoarthritis. And also because in our society you have now more and more young people obese and this overweight problem is very important factor in developing the disease.




-Is there a formula to prevent osteoarthritis?
--I think that everybody will tell you that is the same strategy that one for -preventing other health problems like cardiovascular diseases. People should stay not overweight, should eat normally, avoid to active sports that linked with micro and macro trauma. These are the kind of preventive measures that everybody knows but sometimes are difficult to apply.




-Dou you have any economic impact of the disease in Europe?
--I think that a couple of studies that were made (I have no numbers now to provide you) showed that it is huge because you have so many people affected, the population affected is aging so all this people contribute now to load in terms of economics of the social system.




-What is the latest medicine to stop this degenerative process?
--Well, in Europe, the publication of the EULAR Recommendations for the treatment of knee osteoarthritis in 2003 has listed oral chondroitin sulphate as evidence 1A and strength of recommendation A which represents the highest level for a symptomatic therapeutic strategy. In USA, it is also recommended for knee and hip OA by the most recent OARSI Guidelines in 2010.
Apart from that, my feeling is that we can now answer with yes that chondroitin sulfate can stop the progression of osteoarthritis. We did a couple of studies (Michel et al. 2005 and Kahan et al. 2009) with aim of disease modifying or structure modifying effect of the substance that confirmed chondroitin sulfate can retard the progression of knee OA and can stop the progression in many cases.
Chondroitin sulfate belongs to the oral SYSADOA and the substance does have a delayed mode of action in OA which means that the first effects on pain and mobility can only be assessed after a couple of weeks of therapy (2-3 weeks) in sharp contrast with analgesics and NSAIDs which do act more rapidly (1-3 days). Importantly, when stopped after 3 months of continuous daily administration, CS will present in most cases with a remanent effect which can last for a couple of months in some cases, a feature which is never observed with analgesics and NSAIDs, substances which need to be continuously administered in order to provide relief in pain and increased mobility in OA patients.




**Grateful to contact from BIOIBERICA FARMA

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